The result of smooth muscle cell target protein phosphorylation is a decrease in intracellular calcium, increased efflux of potassium, and deactivation of myosin light chain kinase, ultimately causing smooth muscle relaxation. In the treatment of pulmonary arterial hypertension, patients should also receive monitoring for signs and symptoms of pulmonary edema. It is in the phosphodiesterase-5 inhibitor PDE5-I class of medications. If you often forget doses, it may help to set an alarm to remind you. Its use is not studied in patients with severe hepatic impairment. · Initial dose: 5 or 20 mg orally three times a day, 4 to 6 hours apart. Maximum dose: 20 mg orally three times a day. Injection: Initial dose: or 10 mg IV bolus three times a day. Comments: No greater efficacy was achieved with oral doses higher than the maximum recommended dose. AdRead Customer Reviews & Find Best Sellers. Free, Easy Returns On Millions Of Items. Get Deals and Low Prices On sildenafil mg On has been visited by 1M+ users in the past month. AdOver 50K Customers Save on Prescriptions Each Week Using Free SingleCare® Discount Cards. Save on 50, Brand Name & Generic Drugs With SingleCare®. Get Your Free Rx Coupon Now!Save up-to 80% · Compare prices · NABP certified · Over $1B savedTypes: CVS Pharmacy, Walmart Pharmacy, Walgreens Pharmacy.
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2024
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